Cardiology Journal Articles

• Novel Pulmonary Delivery of Drugs for the Management of AF Currently available oral medications for AF are inefficient and associated with dose-related adverse effects. Might direct pulmonary delivery via inhaler be a viable alternative?
  American Journal of Cardiovascular Drugs, February 03, 2023
• Pharmacogenomics in Stroke and Cardiovascular Disease This review provides an overview of the genetic variants that influence individual responses to aspirin, clopidogrel, warfarin, and statins and the clinical implications for stroke patients.
  Stroke, January 26, 2023
• Therapies Targeting Stroke Recovery This paper presents a concise overview of different modalities of stroke recovery therapeutics, highlighting the need for a personalized medicine approach.
  Stroke, January 12, 2023
• Rate Versus Rhythm Control for AF: Has the Debate Been Settled? This commentary details the pros and cons of rate vs. rhythm control in patients with atrial fibrillation, summarizing recent studies. For which patients is rhythm control preferable?
  Circulation, January 02, 2023
• Tenecteplase Versus Alteplase in Routine Clinical Practice This paper details the results of a hospital network's transition from alteplase to tenecteplase as the standard of care for stroke thrombolysis. How did costs and clinical outcomes compare?
  Stroke, December 29, 2022
• What's EF Got to Do, Got to Do With It? In this commentary, the author presents his thoughts on the relationship of ejection fraction to HFpEF. Do we need to revise current terminology?
  Circulation, December 29, 2022
• Effect of Exercise on BDNF in Stroke Survivors Brain-derived neurotrophic factor has been linked with better functional outcomes after stroke. How might exercise parameters such as intensity and mode influence poststroke BDNF concentration?
  Stroke, December 15, 2022
• Incidence of Stroke in RCTs of COVID-19 Therapeutics Anecdotal reports have suggested that COVID-19 might be a risk factor for stroke. This systematic review aimed to provide an accurate estimate of stroke incidence among patients with COVID-19.
  Stroke, December 06, 2022
• Prolonged and Pronounced LDL Cholesterol Lowering A recent study confirms the notion that longer-term PCSK9 inhibitor use is safe and effective and is associated with better cardiovascular outcomes.
  Circulation, November 25, 2022
• Nelonemdaz in AIS With Endovascular Reperfusion This phase II trial of nelonemdaz, a novel multitarget neuroprotectant, showed promise in patients with acute ischemic stroke receiving endovascular reperfusion therapy.
  Stroke, November 22, 2022
• Apixaban Use in Obese Patients This review summarizes available data on the benefits and risks of apixaban in obese patients. Is dose adjustment necessary in these patients?
  American Journal of Cardiovascular Drugs, November 21, 2022
• Cardiovascular Drug Interactions With NMVr in COVID-19 Patients Nirmatrelvir-ritonavir (NMVr) may have significant interactions with cardiovascular drugs. This paper reviews common ones and the importance of medication reconciliation before initiation of NMVr.
  Journal of the American College of Cardiology, November 14, 2022
• Cumulative Blood Pressure Measurement for CVD Prediction Does cumulative systolic blood pressure load, calculated from serial blood pressure measurements, provide better prediction of major cardiovascular events?
  Journal of the American College of Cardiology, November 07, 2022
• Decoding the Link Between Inflammation and PAH A new study identifies Regnase-1 as a central regulator of inflammation in pulmonary arterial hypertension. What are the clinical implications of this finding?
  Circulation, October 31, 2022
• Antithrombotic Medication in Patients With AF and ICH Is it safe to use oral anticoagulants in patients with atrial fibrillation who have previously survived an intracranial hemorrhage?
  Stroke, October 27, 2022
• Exercise, Cardiovascular Disease, and the Athlete's Heart JACC presents a four-part series on sports cardiology and the impact of physical activity, cardiorespiratory fitness, and exercise training on cardiovascular health.
  Journal of the American College of Cardiology, October 24, 2022
• Empagliflozin and Elderly Patients With HFpEF Do elderly patients with HFpEF benefit as much as younger patients from treatment with an SGLT2 inhibitor? A new study demonstrates its efficacy across all age groups.
  Journal of the American College of Cardiology, October 17, 2022
• Myocarditis After COVID-19 Vaccine and SARS-CoV-2 Infection This study aimed to determine the risk of myocarditis following SARS-CoV2 infection as compared with the risk after sequential COVID-19 vaccination.
  Circulation, October 17, 2022
• Home-Based Transcranial DCS to Enhance Cognition in Stroke Is home-based, remotely supervised transcranial direct current stimulation feasible, safe, and effective for improving poststroke cognitive function in patients with chronic stroke?
  Stroke, October 13, 2022
• HF?EF: The Mysterious Relationship Between HF and EF A new study presents a comprehensive hemodynamic characterization of patients with HFpEF, further elucidating the relationship between LV EF and HFpEF pathophysiology.
  Circulation, October 10, 2022